Pattern of Serum Inhibin B Hormone Secretion in Polycystic Ovarian Disease
نویسندگان
چکیده
Background: Inhibin selectively inhibits FSH but not LH secretion. Data are somewhat conflicting regarding differences in inhibin between normally cycling women and those with polycystic ovarian syndrome (PCOS). The Aim of this Study: Is to study the pattern of inhibinB hormone secretion in cases of PCOS throughout days 3, 5 and 9 of their menstrual cycles. Patients and Methods: The study was performed on 29 women with PCOS, 5ml of blood were collected at days 3, 5 and 9 of the menstrual cycle of each participant for Measurement of inhibin-B hormone. Results: Inhibin B hormone showed an increase in concentration along the studied days of menstrual cycle. There was a highly significant negative correlation between day 3 as well as day 5 inhibin B concentrations and body mass index (BMI), while day 9 inhibin B concentrations showed a non significant correlation with BMI. Day 3, 5 and 9 inhibin B concentrations showed a non significant correlation with age as shown in Table (3). Conclusion: Inhibin B can’t be used alone to diagnose a case of PCOS due to absence of a characteristic pattern of secretion.
منابع مشابه
The effect of exosomes derived from human ovarian epithelial cancer cells on the secretion of AMH and Inhibin in granulosa cells
Exosomes are secreted by different types of cells and known as biological packages. Exosomes have significant role in intercellular communications and involved in the development and progression of various diseases such as cancer. Inhibin B and anti-mullerian hormone (AMH) are markers of granulosa cell tumors (GCT) and due to the role of exosomes in the progression of cancer, in this experiment...
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